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Pattern recognition receptors in liver sinusoidal endothelial cells : Roles in the innate immune system and scavenger functions
Simón-Santamaría, Jaione (Doctoral thesis; Doktorgradsavhandling, 2011-05-05)Effective removal of unwanted self and non-self molecules from blood is essential to keep the organism healthy. Liver sinusoidal endothelial cells (LSECs) have been shown to effectively clear such macromolecules via receptor-mediated endocytosis. The cells express several high affinity endocytosis receptors, including the mannose receptor (MR), and several scavenger receptors (SRs), which are known ...